Endocrine Abstracts

Introduction: Chronic autoimmune hypophysitis is a rare disorder characterised by prolonged inflammation of the pituitary gland, with the commonest subtype being lymphocytic hypophysitis. It is often associated with hypopituitarism and is exceedingly rare in the paediatric population. Here, the authors present a novel case of asymptomatic, chronic hypophysitis in a paediatric patient in association with juvenile idiopathic arthritis (JIA). Case report: A...

Background: Lowe Syndrome is an X-linked recessive genetic disorder caused by OCRL gene mutations, which impair intracellular trafficking processes. Signs are multisystemic, including congenital cataracts, intellectual disability and proximal renal tubulopathy. Short stature is a common association, often attributed to chronic kidney disease through childhood. However, recent evidence suggests that the hypothalamo-pituitary-somatotroph axis may play a role. <p class="abste...